Author

Carl Graham

King's College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Jeffrey SeowiD· 3 shared Katie J. DooresiD· 3 shared Michael H. MalimiD· 2 shared Abbie C. Sibayan· 1 shared Adela Alcolea-Medina· 1 shared Amy L. RobertsiD· 1 shared Anne JacksoniD· 1 shared Antonino ZitoiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

Jeffrey SeowORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Antibody escape drives emergence of diverse spike haplotypes resembling variants of concern in persistent SARS-CoV-2 infections

Luke B. Snell, Suzanne Pickering, Adela Alcolea-Medina, Helena Winstone, Jeffrey Seow, Carl Graham, Lorcan O’Connell, Rahul Batra, Michael H. Malim, Katie J. Doores, Gaia Nebbia, Jonathan D. Edgeworth, Stuart J. D. Neil, Rui Pedro Galão

The paper identifies diverse spike haplotypes in persistent SARS-CoV-2 infections that show immune escape mechanisms similar to variants of concern.

Cell Reports Medicine · Feb 1, 2026Peer-reviewedMicrobiology

Spike-specific IgG4 generated post BNT162b2 mRNA vaccination is inhibitory when directly competing with functional IgG subclasses

Jerry C H Tam, Abbie C. Sibayan, Jeffrey Seow, Carl Graham, Ashwini Kurshan, Blair Merrick, Richard James Stanton, Katie J. Doores

This study shows that Spike-specific IgG4 generated after BNT162b2 vaccination can inhibit effector functions when competing with other IgG subclasses, despite overall increased neutralization and effector activity.

Cell Reports · Jul 1, 2025Peer-reviewedImmunology

ACE2 expression in adipose tissue is associated with COVID-19 cardio-metabolic risk factors and cell type composition

Julia S. El-Sayed Moustafa, Anne Jackson, Sarah M. Brotman, Li Guan, Sergio Villicaña, Amy L. Roberts, Antonino Zito, Lori L. Bonnycastle, Michael R. Erdos, Narisu Narisu, Heather M. Stringham, Ryan Welch, Tingfen Yan, Timo Antero Lakka, Stephen C.J. Parker, , Kerrin S. Small

The paper examines the association between adipose tissue ACE2 expression and cardio-metabolic risk factors, finding lower ACE2 levels linked to T2D, obesity, and inflammation-related cell type changes.

International Journal of Obesity · May 19, 2022Peer-reviewedGenetic & Genomic Medicine