Cullen B. Young

The paper introduces FORCENET, an implantable sensor network that maps intercellular forces in living embryos, revealing coordinated mechanical patterns regulated by developmental signaling.

This paper introduces PEARLS, a new light sheet microscopy technique that reduces photobleaching and improves aberration resilience for 3D subcellular imaging in complex environments.

This paper introduces CODEMax and CODEMax(exo+) genome editing systems that enable efficient and precise search-and-replace editing in human cells with reduced off-target effects.

A novel Cfap298 mutation disrupts left-right patterning in mice by impairing ciliary motility, revealing a conserved protein region essential for this function across species.

The paper shows that gene-teratogen interactions affect birth defect penetrance by altering Hedgehog signaling through the MMM complex and SMO degradation.

This study identifies a ubiquitin-based genetic mechanism linking Megf8 and Mgrn1 mutations to congenital heart defects and heterotaxy through altered Hedgehog signaling.