Author

Vladimír Šrámek

Masaryk UniversityORCID 0000-0002-6283-4073Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Jan FričiD· 2 shared Julie ŠtíchováiD· 2 shared Kamila BendíčkováiD· 2 shared Marcela Hortová KohoutkováiD· 2 shared Marcela VlkováiD· 2 shared Marco De ZuaniiD· 2 shared Martin HelániD· 2 shared Tomáš TomášiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersImmunology

Jan FričORCID

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2 papers

Recent·Most cited

Sepsis induces long-term reprogramming of human HSPCs and drives myeloid dysregulation in sepsis survivors

Marco De Zuani, Petra Lázničková, Marcela Hortová Kohoutková, Veronika Bosáková, Ivana Andrejčinová, Natália Vadovičová, Veronika Tomášková, Alexandra Mýtniková, Julie Štíchová, Tomáš Tomáš, Jiří Hrdý, Kristýna Boráková, Stjepan Uldrijan, Marcela Vlková, Vladimír Šrámek, , Jan Frič

This study shows sepsis causes long-term changes in human HSPCs, leading to immune dysregulation in survivors through altered myeloid progeny and metabolic reprogramming.

Journal of Inflammation · Jan 27, 2026Peer-reviewedImmunology

Long-term immune changes after COVID-19 and the effect of BCG vaccination and latent infections on disease severity

Kamila Bendíčková, Ioanna Papatheodorou, Gabriela Blažková, Martin Helán, Michaela Haláková, Petr Bednář, Erin Spearing, Lucie Obermannová, Julie Štíchová, Monika Dvořáková Heroldová, Tomáš Tomáš, Roman Panovský, Vladimír Šrámek, Marco De Zuani, Marcela Vlková, , Jan Frič

This study examines long-term immune changes post-COVID-19 and the impact of BCG vaccination and latent infections on disease severity.

Clinical & Translational Immunology · Jan 1, 2025Peer-reviewedImmunology