Author

Anne Talkington

University of VirginiaORCID 0000-0002-6296-6754Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Ben Z. StangeriD· 1 shared Britney Chu· 1 shared Jason J. Wieder· 1 shared Jason Robert PitarresiiD· 1 shared Karl M. Kowalewski· 1 shared Kia Z. Perez-ValeiD· 1 shared Matthew J. LazzaraiD· 1 shared Rosalie C. SearsiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ben Z. StangerORCID

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1 paper

Recent·Most cited

Hypoxia-induced histone methylation and NF-κB activation in pancreas cancer fibroblasts promote EMT-supportive growth factor secretion

Karl M. Kowalewski, Sara J. Adair, Anne Talkington, Jason J. Wieder, Jason Robert Pitarresi, Kia Z. Perez-Vale, Britney Chu, Sepideh Dolatshahi, Rosalie C. Sears, Ben Z. Stanger, Todd W. Bauer, Matthew J. Lazzara

The paper shows hypoxic fibroblasts in pancreas cancer use histone methylation and ROS-mediated NF-κB activation to produce growth factors that drive epithelial-mesenchymal transition in malignant cells.

bioRxiv · Jan 30, 2025 · PreprintCancer Biology