Sepideh Dolatshahi

The paper identifies multi-factorial regulatory networks governing placental antibody transfer, showing how Fc receptor expression, IgG subclass, and clinical covariates interact to influence transfer efficiency.

This study identifies LAG3+ CD8+ T cells as key effectors in bispecific antibody armed T cell therapy for HR+/HER2- breast cancer and shows how checkpoint inhibitors can enhance their anti-tumor function.

The paper identifies distinct type 1 immune networks associated with varying severities of restrictive lung disease following COVID-19.

The paper shows hypoxic fibroblasts in pancreas cancer use histone methylation and ROS-mediated NF-κB activation to produce growth factors that drive epithelial-mesenchymal transition in malignant cells.

The paper examines the relationship between MHC-I expression, NK cell, and CD8 T cell infiltration in NSCLC, finding that higher infiltration correlates with improved survival despite MHC-I loss.

The paper develops a quantitative mechanistic model of placental IgG transfer to identify key determinants and inform personalized prenatal immunization strategies.