Pujan Shrestha

This paper models tumor growth dynamics using a controlled birth-death process to show how cost structures and constraints influence population-level regulation of proliferation and apoptosis.

This study shows that higher ploidy reduces gemcitabine potency and delays cell death by altering drug exposure kinetics and response timing.

This paper develops a coupled SDE-ODE model to infer tumor burden from biomarker signals by linking tumor-immune dynamics to ctDNA release.

This paper introduces a stochastic model to study cancer immune escape dynamics, showing how immunomodulation in the tumor microenvironment affects disease recurrence timing in bladder and breast cancer.