Magdalena B. Murray

This study investigates how proteasome inhibition affects ferroptosis sensitivity using combined experimental and modeling approaches, revealing both sensitizing and desensitizing effects on different ferroptosis triggers.

This study shows that larger cells are more resistant to ferroptosis due to higher glutathione levels and lower lipid peroxides.

This study shows that GPX4 inhibitor sensitivity differs between 2D and 3D cultures due to lipid composition changes, with 3D cultures showing resistance through PUFA displacement by MUFAs.