Krystina J. Szylo

The paper identifies metabolic differences between ASCL1-high and low SCLC cells, showing that ASCL1-high cells resist ferroptosis via BH4/BH2 antioxidants and are vulnerable to combined cysteine depletion and BH4/BH2 inhibition.

This study investigates how proteasome inhibition affects ferroptosis sensitivity using combined experimental and modeling approaches, revealing both sensitizing and desensitizing effects on different ferroptosis triggers.

The paper links lower plasma plasmalogen levels to increased risk of lymph node positive breast cancer in humans and mice, showing dietary PUFA depletion promotes cancer survival in lymph nodes.