ImmunologyJCI InsightPeer-reviewed
Reduced late endosome/lysosome function promotes SLE through chronic PI3k activity and SHP-1/SHIP-1 defects
SunAh Kang, Andrew J. Monteith, Liubov S Arbeeva…·Barbara J. Vilen
This study identifies reduced late endosome/lysosome function in SLE patients, linked to chronic PI3k activity and SHP-1/SHIP-1 defects, and suggests it as a potential biomarker.