Author

Virginie Coustou

Centre National de la Recherche ScientifiqueORCID 0000-0002-6327-2113Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:fungi (other)· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Organism:E. coli· 1

Frequent Co-Authors

Sven J. SaupeiD· 3 shared Alexandra Granger‐FarbosiD· 2 shared Aaron A. VoganiD· 1 shared Alfons J. M. DebetsiD· 1 shared Antoine LoquetiD· 1 shared Aurélie Massoni‐Laporte· 1 shared Bénédicte SaliniD· 1 shared Birgit HabensteiniD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMicrobiology

Sven J. SaupeORCID

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3 papers

Recent·Most cited

Amyloid signaling in antiphage defense

Léa Ibarlosa, Sonia Dheur, C. Sánchez, Seamoon Deb, Alexandra Granger‐Farbos, Virginie Coustou, Mélanie Berbon, Aurélie Massoni‐Laporte, Bénédicte Salin, Corinne Blancard, Claire Saragaglia, Xavière Menatong Tene, Nicolas Dufour, Ombeline Rossier, Birgit Habenstein, , Sven J. Saupe

The paper describes an amyloid-based signal transduction mechanism in Escherichia coli's antiphage defense system, showing functional interchangeability between Bab and fungal HET-S amyloids.

Nature Microbiology · Aug 14, 2025Peer-reviewedMicrobiology

Exploring a diverse world of effector domains and amyloid signaling motifs in fungal NLR proteins

Jakub Wiktor Wojciechowski, Emirhan Tekoglu, Marlena Gąsior‐Głogowska, Virginie Coustou, Natalia Szulc, Monika Szefczyk, Marta Kopaczyńska, Sven J. Saupe, Witold Dyrka

The paper analyzes fungal NLR proteins to identify effector domains and amyloid signaling motifs using bioinformatics and structural prediction tools, revealing new domains and expanded amyloid motif families.

PLoS Computational Biology · Dec 21, 2022Peer-reviewedBioinformatics

Combinations of Spok genes create multiple meiotic drivers in Podospora

Aaron A. Vogan, Sandra Lorena Ament‐Velásquez, Alexandra Granger‐Farbos, Jesper Svedberg, Eric Bastiaans, Alfons J. M. Debets, Virginie Coustou, Hélène Yvanne, Corinne Clavé, Sven J. Saupe, Hanna Johannesson

The paper identifies Spok genes as the molecular basis of meiotic drivers in Podospora anserina and shows their role in spore killing and resistance through distinct domains.

eLife · Jul 25, 2019Peer-reviewedGenetics