Author
Leiden University Medical CenterORCID 0000-0002-6338-4975Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Pingzhuang Ge, Fatema‐Zahra M. Rashid, Luuk Gaarthuis…·Remus Thei Dame
This study investigates how H-NS and StpA regulate gene expression in E. coli under acid and osmotic stress by analyzing transcription, DNA binding, and chromatin structure at specific operons.
Minkang Tan, Shengnan Sun, Yuchen Liu…·Baoxu Pang
This study shows anthracycline drugs disrupt 3D chromatin structure by interfering with CTCF binding, altering gene regulation and clinical outcomes in AML.
Minkang Tan, Jan van Weerd, Alper Yavas, Baoxu Pang
The paper identifies non-coding variants affecting silencer function in blood cells, showing their impact on gene expression and erythroid differentiation.
Shengnan Sun, Renhong Sun, Minkang Tan…·Baoxu Pang
This paper develops a PROTAC molecule that degrades SpCas9 proteins, enhancing CRISPR genome editing precision by reducing off-target effects.