Baoxu Pang

This study investigates how H-NS and StpA regulate gene expression in E. coli under acid and osmotic stress by analyzing transcription, DNA binding, and chromatin structure at specific operons.

This study shows anthracycline drugs disrupt 3D chromatin structure by interfering with CTCF binding, altering gene regulation and clinical outcomes in AML.

The paper identifies non-coding variants affecting silencer function in blood cells, showing their impact on gene expression and erythroid differentiation.

This paper develops a PROTAC molecule that degrades SpCas9 proteins, enhancing CRISPR genome editing precision by reducing off-target effects.