Alicia Maciá Valero

This study resolves high-resolution structures of the C. auris ribosome in complex with three inhibitors, revealing unique features that may inform antifungal therapy development.

The paper develops a workflow to identify and characterize antifungal environmental yeasts, finding 31% of 681 isolates show antagonism against pathogens, with 25% potentially secreting toxic proteins.

The paper characterizes pulcherriminic acid biosynthesis in yeast using a heterologous system, showing that K. lactis genes produce faster acid than Metschnikowia genes and that Pul3 mediates both uptake and export of the compound.