Conkazal-M1 from the MKAVA family of conotoxins - a dual-function protease inhibitor and neuroactive peptide
Celeste Menuet Hackney, Thomas Lund Koch, Nicklas Lund Ryding, Aymeric Rogalski, Kevin Chase, Matías Leonel Giglio, Samuel S. Espino, Zildjian G. Acyatan, Maren Watkins, Baldomero M. Olivera, Helena Safavi-Hemami, Kaare Teilum, Lars Ellgaard
This study characterizes conkazal-M1, a conotoxin from Conus magus, showing it acts as both a protease inhibitor and a neuroactive peptide.
Protein Science · Apr 22, 2026Peer-reviewedBiochemistry