Lars Ellgaard

Proteome analyses reveal Endoplasmic Reticulum stress-induced changes in protein abundance associated with Ube2j2 deficiency in human cell culture

The paper uses mass spectrometry to analyze how Ube2j2 deficiency affects the proteome under ER stress in human cells, identifying new pathways and functions associated with Ube2j2.

Conkazal-M1 from the MKAVA family of conotoxins - a dual-function protease inhibitor and neuroactive peptide

This study characterizes conkazal-M1, a conotoxin from Conus magus, showing it acts as both a protease inhibitor and a neuroactive peptide.

Structural similarities reveal an expansive conotoxin family with a two-finger toxin fold

The paper uses structural bioinformatics to identify a new conotoxin family with a two-finger toxin fold, revealing evolutionary relationships among rapidly evolving genes.

Intermolecular Disulfide-Bond Formation In Human FICD Modulates The Activity Of The Hyperactive E234G Mutant

This paper shows that FICD's adenylyltransferase activity induces ER stress and that its disulfide-bond formation modulates its activity in the context of a hyperactive mutant.