Author

Nancy De La Cruz

The University of Texas Southwestern Medical CenterORCID 0000-0002-6358-7318Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Biophysics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Alejandro Aguilera-CastrejoniD· 2 shared Andrea Woods· 2 shared Ashley SolmonsoniD· 2 shared Benjamin R. SabariiD· 2 shared Dmitry Lokshtanov· 2 shared Jacob H. HannaiD· 2 shared Maria E. Florian RodrigueziD· 2 shared Nawal A. KhaniD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersDevelopmental Biology

Alejandro Aguilera-CastrejonORCID

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4 papers

Recent·Most cited

Developmental BiologybioRxivPreprintMar 18, 2026

Midgestation metabolic constraint in purine metabolism drives distinct strategies for placenta and fetal growth

Weizhi Xu, Nancy De La Cruz, Andrea Woods…·Ashley Solmonson

The paper shows that midgestational metabolic constraints in purine metabolism drive distinct strategies for placenta and fetal growth in mice and humans.

1 citation

mousehuman

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Developmental BiologybioRxivPreprintMar 18, 2026

Reconstituting Mouse Embryogenesis Ex Utero from Gastrulation to Fetal Development Reveals Maternally Independent Metabolic Programs

Dmitry Lokshtanov, Shihong Max Gao, Weizhi Xu…·Alejandro Aguilera-Castrejon

This paper uses ex utero culture to study mouse embryogenesis from gastrulation to fetal development, revealing metabolically independent programs and environmental influences on metabolic transitions.

1 citation

mousebulk RNA-seq

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BiophysicsCommunications ChemistryPeer-reviewedOct 13, 2025

Sequence-based prediction of condensate composition reveals that specificity can emerge from multivalent interactions among disordered regions

Jonas Wessén, Nancy De La Cruz, Heankel Lyons…·Benjamin R. Sabari

The paper shows that multivalent interactions among disordered regions can explain condensate specificity, using a polymer physics model and experimental validation.

11 citations

statistical model

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Molecular BiologyeLifePeer-reviewedApr 7, 2025

N6-methyladenosine in DNA promotes genome stability

Brooke A. Conti, Leo Novikov, Deyan Tong…·Mariano Oppikofer

The paper identifies METTL3 and N6-methyladenosine (6mA) as factors promoting genome stability by repairing DNA base lesions.

7 citations

humanDNA methylation

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