Author
University of Milano-BicoccaORCID 0000-0002-6365-5149Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Nagarajan Pattabiraman, Cosimo Lobello, David Rushmore…·Johnvesly Basappa
This paper identifies VCB1, a novel ACLY inhibitor, which overcomes TKI resistance in lymphoma by disrupting lipid and nucleotide metabolism, ISR, and redox homeostasis.
Johnvesly Basappa, Cosimo Lobello, Anneliese M. Faustino…·Mariusz A. Wasik
This study identifies tyrosine phosphorylation and dimerization as cooperative mechanisms activating NAMPT, enhancing NAD+ synthesis and cancer cell growth.
Nagarajan Pattabiraman, Cosimo Lobello, David Rushmore…·Johnvesly Basappa
Diletta Fontana, Ilaria Crespiatico, Valentina Crippa…·Daniele Ramazzotti
This study identifies cancer type-specific evolutionary signatures using genomic data from over 35,000 patients, revealing patterns of driver mutation acquisition linked to prognosis.
Mattia Zaghi, Federica Banfi, Luca Massimino…·Alessandro Sessa
The paper shows that SET levels influence enhancer usage during cell fate acquisition, leading to altered gene regulation and contributing to disease.