Eric L. Bruger

This study identifies CstR as a key regulator in Methylobacterium extorquens that coordinates carbon source transitions and stress responses, with loss-of-function mutations improving metabolic flexibility but reducing stress resilience.

This study shows that reducing peptide deformylase activity in Methylobacterium extorquens increases formaldehyde resistance, with pleiotropic effects and tradeoffs in heat shock resistance.