Zeyuan Zhang

The paper shows that inhibiting 15-PGDH in geriatric mice restores muscle strength by increasing PGE2 levels, which activates an IGF1-mediated circuit for muscle growth.

The paper shows that inhibiting 15-PGDH counteracts muscle regeneration deficits caused by GLP-1 receptor agonist-induced weight loss in mice.

This study investigates the role of BAT ADH5 in aging, showing that its loss accelerates BAT senescence and metabolic decline, while HSF1 activation mitigates these effects.

This study identifies GILT's role in maintaining cardiac immuno-metabolic homeostasis, showing its deficiency leads to heart failure in mice.

This study shows ADH5 maintains BAT metabolic homeostasis by regulating S-nitrosylation and thermogenesis under obesity and cold stress.

The paper identifies a micropeptide encoded by a long noncoding RNA that regulates pancreatic β-cell function and insulin secretion.