Biyi Chen

This study shows that PHB complex ablation in cardiomyocytes leads to mTORC1 activation and metabolic reprogramming, causing dilated cardiomyopathy and mortality in mice.

This study identifies GILT's role in maintaining cardiac immuno-metabolic homeostasis, showing its deficiency leads to heart failure in mice.

The paper identifies a micropeptide encoded by a long noncoding RNA that regulates pancreatic β-cell function and insulin secretion.

This study shows that O-GlcNAcylation and oxidative stress via CaMKII contribute to atrial fibrillation in type 1 and type 2 diabetes through distinct mechanisms.