Author

Qingwen Qian

University of Iowa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 3 Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Approach:statistical model· 2

Frequent Co-Authors

Ling YangiD· 5 shared Mark LiiD· 4 shared Zeyuan ZhangiD· 4 shared Biyi CheniD· 2 shared Long‐Sheng SongiD· 2 shared Matthew J. PotthoffiD· 2 shared Sara C. Sebag· 2 shared Vitor Agnew LiraiD· 2 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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5 shared papersMolecular Biology

Ling YangORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Thermogenic Adipose ADH5 Counteracts Age-related Metabolic Decline

Sara C. Sebag, Tate J. Neff, Qingwen Qian, Arvand Asghari, Zhuozhi Wang, Zeyuan Zhang, Mark Li, Meihua Hao, Vitor Agnew Lira, Hongli Sun, Matthew J. Potthoff, Ling Yang

This study investigates the role of BAT ADH5 in aging, showing that its loss accelerates BAT senescence and metabolic decline, while HSF1 activation mitigates these effects.

bioRxiv · Jul 1, 2025 · PreprintPhysiology

The mitochondrial dicarboxylate carrier mediates in vivo hepatic gluconeogenesis

Daniel J. Pape, Kelly C. Falls-Hubert, Ronald A. Merrill, Adnan Ahmed, Qingwen Qian, Gavin R. McGivney, Paulina Sobieralski, Adam J. Rauckhorst, Ling Yang, Eric B. Taylor

This study shows that the mitochondrial dicarboxylate carrier mediates hepatic gluconeogenesis from lactate/pyruvate and contributes to glucose homeostasis in a T2D mouse model.

bioRxiv · Sep 12, 2024 · PreprintBiochemistry

Gamma-interferon-inducible lysosomal thiol reductase maintains cardiac immuno-metabolic homeostasis in heart failure

Mark Li, Jinxi Wang, Qingwen Qian, Biyi Chen, Zeyuan Zhang, Elizabeth Barroso, Yuan Zhang, Duane D. Hall, E. Dale Abel, Long‐Sheng Song, Ling Yang

This study identifies GILT's role in maintaining cardiac immuno-metabolic homeostasis, showing its deficiency leads to heart failure in mice.

bioRxiv · Jul 3, 2022 · PreprintMolecular Biology

ADH5-mediated NO Bioactivity Maintains Metabolic Homeostasis in Brown Adipose Tissue

Sara C. Sebag, Zeyuan Zhang, Qingwen Qian, Mark Li, Zhiyong Zhu, Mikako Harata, Wenxian Li, Leonid V. Zingman, Limin Liu, Vitor Agnew Lira, Matthew J. Potthoff, Alexander Bartelt, Ling Yang

This study shows ADH5 maintains BAT metabolic homeostasis by regulating S-nitrosylation and thermogenesis under obesity and cold stress.

Cell Reports · Nov 1, 2021Peer-reviewedMolecular Biology

A putative long noncoding RNA-encoded micropeptide maintains cellular homeostasis in pancreatic β-cells

Mark Li, Fan Shao, Qingwen Qian, Wenjie Yu, Zeyuan Zhang, Biyi Chen, Dan Su, Yuwei Guo, An-Vi Phan, Long‐Sheng Song, Samuel B. Stephens, Julien A. Sebag, Yumi Imai, Ling Yang, Huojun Cao

The paper identifies a micropeptide encoded by a long noncoding RNA that regulates pancreatic β-cell function and insulin secretion.

Molecular Therapy — Nucleic Acids · Jul 16, 2021Peer-reviewedMolecular Biology