Author

Komal Pekhale

The University of Texas Southwestern Medical CenterORCID 0000-0002-6372-3690Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Cristel V. CamachoiD· 1 shared Jonathan C AbshieriD· 1 shared Lu Yang· 1 shared Morgan DasovichiD· 1 shared Sridevi ChallaiD· 1 shared W. Lee KrausiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

Cristel V. CamachoORCID

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1 paper

Recent·Most cited

Cancer BiologyJournal of Biological ChemistryPeer-reviewedSep 8, 2026

PARP16 is a Druggable Regulator of Ribosome MARylation and Protein Homeostasis in Ovarian Cancer Cells

Sridevi Challa, Morgan Dasovich, Jonathan C Abshier…·W. Lee Kraus

This study investigates PARP16's role in ovarian cancer by showing that inhibiting it with DB008 disrupts ribosome MARylation, impairs protein homeostasis, and reduces tumor growth.

DOI 10.1016/j.jbc.2026.113540

humanproteomics

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