Author

Rebecca Briggs

Queen's University BelfastORCID 0000-0002-6399-196XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Carl S. GoodyeariD· 1 shared Ebubechukwu NwarunmaiD· 1 shared Glen WattiD· 1 shared Helen WheadoniD· 1 shared Katerina E. MiariiD· 1 shared Katrina M. LappiniD· 1 shared Ken MillsiD· 1 shared Ki Jun LeeiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Carl S. GoodyearORCID

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1 paper

Recent·Most cited

LIMK Inhibition and Metformin Block Mitochondrial Transfer Overcoming Macrophage Driven Therapy Resistance in Acute Myeloid Leukaemia

Ebubechukwu Nwarunma, Katerina E. Miari, Αθανασία Παπαδοπούλου, Stefan Corradini, Glen Watt, Samantha Hurwitz, Tatiana Fourfouris, Ki Jun Lee, Xenia Bubnova, Rebecca Briggs, Carl S. Goodyear, Theodoros Simakou, Marcus Doohan, Lucy MacDonald, Mariola Kurowska‐Stolarska, , Mark Thomas Shaw Williams

This study identifies mitochondrial transfer from M2-like macrophages to AML cells as a mechanism of chemoresistance, showing that LIMK inhibition and metformin block this transfer and restore chemosensitivity.

bioRxiv · Feb 5, 2026 · PreprintCancer Biology