Carl S. Goodyear

This study compares chondrogenic differentiation of iPSC-derived chondroprogenitors (iCPs) and MSCs in alginate hydrogels, finding iCPs show superior cartilage formation with enhanced matrix composition.

The paper decomposes trabecular separation into local trabecular spacing and marrow cavity expansion to better understand metaphyseal bone changes in osteoporosis, spinal cord injury, ovariectomy, and ageing.

This study identifies mitochondrial transfer from M2-like macrophages to AML cells as a mechanism of chemoresistance, showing that LIMK inhibition and metformin block this transfer and restore chemosensitivity.

This study identifies PIEZO1 as a mechanosensor driving inflammation-permissive macrophage phenotypes in synovial tissue, contributing to joint inflammation in RA.

RNAcare integrates clinical and transcriptomic data for bulk RNA-Seq analysis, enabling hypothesis generation about gene expression-clinical symptom relationships in rheumatoid arthritis.