Author

Pamela N Romero Villela

University of Colorado BoulderORCID 0000-0002-6401-3260Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 4

Signature Assays, Organisms & Methods

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Assay:GWAS summary statistics· 4 Organism:human· 4 Approach:statistical model· 4 Research Focus:GWAS / association mapping· 3 Research Focus:benchmarking· 1

Frequent Co-Authors

Alexander Samir HatoumiD· 3 shared Arpana Agrawal AiD· 3 shared Emma C. JohnsoniD· 3 shared Alex P. MilleriD· 2 shared Jared V. BalbonaiD· 2 shared Pamela A. F. MaddeniD· 2 shared Alexandros GiannelisiD· 1 shared Andrew C. HeathiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Alexander Samir HatoumORCID

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4 papers

Recent·Most cited

Phenotypic and genetic characterization of different modes of lifetime nicotine use in the All of Us Research Program

Feiyang Huang, Pamela N Romero Villela, Zhen Luo, Alex P. Miller, Pamela A. F. Madden, Arpana Agrawal A, Alexander Samir Hatoum, Emma C. Johnson

The paper identifies genetic risks and phenotypic differences across five nicotine use modes using GWAS in the All of Us Research Program.

medRxiv · Sep 17, 2026 · PreprintGenetic & Genomic Medicine

Multi-ancestral genome-wide study of chronic pain reveals widespread genetic correlations with mental and physical health traits

Pamela N Romero Villela, Jared V. Balbona, Nithya Sarabudla, Alexander Samir Hatoum, Simon Haroutounian, Arpana Agrawal A, Emma C. Johnson

This study performs a genome-wide association study of chronic pain across six ancestries, identifying two significant loci and showing genetic correlations with mental and physical health traits.

medRxiv · Sep 29, 2025 · PreprintGenetic & Genomic Medicine

Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits.

Emma C. Johnson, Dongbing Lai, Jared V. Balbona, Alex P. Miller, Alexander Samir Hatoum, Joseph D. Deak, Mariela V. Jennings, David A. A. Baranger, Marco Galimberti, Kittipong Sanichwankul, Thorgeir Elís Thorgeirsson, Sarah M. C. Colbert, Keyrun Adhikari, Anna R. Docherty, Louisa J Degenhardt, , Arpana Agrawal A

This study performs a multi-ancestral GWAS of DSM-defined nicotine dependence, finding genetic correlations with other substance use disorders and health traits, and identifying a strong general addiction liability factor.

Psychological Medicine · Jan 1, 2025Peer-reviewedGenetic & Genomic Medicine

Little Evidence of Modified Genetic Effect of rs16969968 on Heavy Smoking Based on Age of Onset of Smoking

Christine Adjangba, Richard Border, Pamela N Romero Villela, Marissa A. Ehringer, Luke M. Evans

The paper replicates main effects of rs16969968 and age of smoking onset on smoking quantity but fails to replicate their interaction effect.

Nicotine & Tobacco Research · Nov 3, 2020Peer-reviewedGenetic & Genomic Medicine