Keyrun Adhikari

Rare loss-of-function variants in POLD1, PMS1 and FAN1 modify age at onset of motor symptoms in Huntington's disease

Multi-ancestry epigenome wide association study of generalized anxiety disorder

This study identifies 49 CpG sites associated with generalized anxiety disorder across three ancestries but finds limited replication in an independent cohort.

Genetics of SSRI Antidepressant Use and Relationship to Psychiatric and Medical Traits

This study identifies 40 genome-wide significant loci for SSRI use and finds genetic correlations with psychiatric and medical traits, suggesting SSRI use is a proxy for MDD with distinct genetic architecture.

A contextual genomic perspective on physical activity and its relationship to health, well-being and illness

This study investigates the genetic basis of physical activity across different contexts and finds that leisure-time activity has distinct genetic influences and protective health effects.

Multi-ancestry genetic architecture of sleep duration and its relationship to other sleep and psychiatric phenotypes

This paper conducts a multi-ancestry GWAS of sleep duration, identifying 234 genome-wide significant loci and showing distinct genetic architecture from other sleep and psychiatric traits.

Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits.

This study performs a multi-ancestral GWAS of DSM-defined nicotine dependence, finding genetic correlations with other substance use disorders and health traits, and identifying a strong general addiction liability factor.

A genome-wide investigation into the underlying genetic architecture of personality traits and overlap with psychopathology.

This study conducts a genome-wide association analysis of the Big Five personality traits, identifying novel genetic loci and associations with psychiatric traits.

Genomewide association study of epiretinal membrane: discovery of significant risk loci in each of three American populations

This paper conducts a genome-wide association study (GWAS) of epiretinal membrane (ERM) in three American populations, identifying significant risk loci and genetic correlations with other traits.

Understanding the comorbidity between posttraumatic stress severity and coronary artery disease using genome-wide information and electronic health records

This study investigates the genetic and longitudinal relationship between posttraumatic stress disorder and coronary artery disease using genome-wide data and electronic health records.