Author

Brenda Aguilar

City Of Hope National Medical CenterORCID 0000-0002-6408-8422Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Christine E. BrowniD· 3 shared Renate StarriD· 3 shared Behnam BadieiD· 2 shared Darya AlizadehiD· 2 shared Heini M. NatriiD· 2 shared Jonathan C. HibbardiD· 2 shared Maryam AftabizadehiD· 2 shared Nicholas E. BanovichiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersCancer Biology

Christine E. BrownORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 3, 2026

Patient-Derived Glioma Models Preserve Tumor Heterogeneity and Identify Stearoyl-CoA Desaturase1 (SCD1) as a Candidate Biomarker for Precision Immunotherapy

Margarita Gutova, Eric Ma, Heini M. Natri…·Christine E. Brown

DOI 10.64898/2026.09.01.748569

humanbulk RNA-seq

𝕏 PostBluesky

BioengineeringCancer Immunology ResearchPeer-reviewedAug 4, 2026

Meditope-Enabled Chimeric Antigen Receptors Facilitate Plug-and-Play Control of T Cells

Cheng-Fu Kuo, Zhen Tong, Yi‐Chiu Kuo…·Christine E. Brown

This study develops meditope-enabled CARs to improve T cell functionality and address tumor heterogeneity in CAR therapy.

1 citation

𝕏 PostBluesky

Cancer BiologybioRxivPreprintApr 1, 2025

Overcoming myeloid-driven resistance to CAR T therapy by targeting SPP1

Sharareh Gholamin, Heini M. Natri, Yuqi Zhao…·Christine E. Brown

This study identifies SPP1+ macrophages as key drivers of resistance to CAR T therapy in solid tumors and shows that targeting SPP1 can overcome this resistance.

4 citations

𝕏 PostBluesky