Author
City Of Hope National Medical CenterORCID 0000-0002-2200-6900Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Darya Alizadeh, Robyn A. Wong, Madeleine S. Maker…·Christine E. Brown
This study shows that targeting the TGFβ pathway improves CAR T cell efficacy in glioblastoma by enhancing antitumor activity and modulating the tumor microenvironment.
Margarita Gutova, Eric Ma, Heini M. Natri…·Christine E. Brown
Cheng-Fu Kuo, Zhen Tong, Yi‐Chiu Kuo…·Christine E. Brown
This study develops meditope-enabled CARs to improve T cell functionality and address tumor heterogeneity in CAR therapy.
Sharareh Gholamin, Heini M. Natri, Yuqi Zhao…·Christine E. Brown
This study identifies SPP1+ macrophages as key drivers of resistance to CAR T therapy in solid tumors and shows that targeting SPP1 can overcome this resistance.