Cell BiologybioRxivPreprint
Rapamycin reverts cavernoma endothelial cell phenotype and when combined with lapatinib ameliorates chronic lesions
Mar García-Colomer, José E Martínez, Luis Antonio Díaz-Gómez…·Juan B. Zalvide
This study shows rapamycin reverses gene expression in Ccm3-deficient endothelial cells and, when combined with lapatinib, reduces lesion volume in a chronic CCM model.
DOI 10.1101/2025.11.03.686432