Zhanghua Chen

Validation of human telomere length trans-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as novel human telomere length regulation genes

The paper validates novel telomere length regulation genes POP5 and KBTBD6 identified through trans-ancestry GWAS using functional experiments in blood cells.

Novel genetic determinants of telomere length from a trans-ethnic analysis of 109,122 whole genome sequences in TOPMed

This study identifies 59 sentinel variants and two novel genes associated with telomere length using whole genome sequences from 109,122 trans-ethnic individuals.

Gene co-expression networks in whole blood implicate multiple interrelated molecular pathways in obese asthma

The paper uses gene co-expression networks in whole blood to identify molecular pathways associated with obese asthma, finding four modules linked to obesity and enriched for inflammatory pathways.