Author

Yuhong Li

Wuhan UniversityORCID 0000-0002-6435-2027Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yuhong Li1 paper · Huazhong University of Science and Technology

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Fangfang Yao· 2 shared Hongping WeiiD· 2 shared Jiajun HeiD· 2 shared F Chen· 1 shared Fangyuan Chen· 1 shared Hang Yang· 1 shared Jiannan ZhouiD· 1 shared Raphael NyaruabaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

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2 shared papersMicrobiology

Fangfang Yao

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintApr 29, 2026

Engineering Dual-Target Chimeric Lysins for Synergistic Eradication of Porphyromonas gingivalis

Fangfang Yao, Jiajun He, Fangyuan Chen…·Yuhong Li

This study engineers dual-target chimeric lysins to eradicate Porphyromonas gingivalis in periodontitis, showing significant bactericidal activity and reduced inflammation in a mouse model.

DOI 10.64898/2026.04.27.720852

mouseexperimental assay

MicrobiologybioRxivPreprintApr 13, 2026

Structure-based similarity network accelerates the discovery of lysins as oral microbiome modulators targeting periodontal pathogens

Fangfang Yao, Jiajun He, Raphael Nyaruaba…·Yuhong Li

The paper identifies potent periodontal lysins using a structure-based pipeline and shows LysPd078 effectively modulates oral microbiome communities in preclinical models.

2 citations

mouseprotein structure