GenomicsbioRxivPreprint
Single-cell Individual Complete mtDNA Sequencing Uncovers Hidden Mitochondrial Heterogeneity in Human and Mouse Oocytes
Chongwei Bi, Lin Wang, Yong Fan…·Mo Li
This paper introduces iMiGseq, a method for ultra-sensitive mtDNA sequencing in oocytes, revealing hidden heterogeneity and deleterious variants in human and mouse samples.