A Versatile Antibody Capture System that Drives Precise In Vivo Delivery of mRNA loaded Lipid Nanoparticles and Enhances Gene Expression
Moore Z. Chen, Daniel Yuen, Victoria M. McLeod, Ken W. Yong, Cameron H. Smyth, Bruna Rossi Herling, Thomas J. Payne, Stewart A. Fabb, Matthew J. Belousoff, Azizah Algarni, Patrick Michael Sexton, Christopher J. H. Porter, Colin William Pouton, Angus P. R. Johnston
This paper introduces an antibody capture system for LNPs that enhances mRNA delivery and gene expression by enabling precise targeting to T cells with minimal off-target effects.
Nature Nanotechnology · Aug 4, 2025Peer-reviewedBioengineering