Author

Marcel Brun

National University of Mar del PlataORCID 0000-0002-6452-5856Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1 Assay:protein sequence· 1 Research Focus:sequence-to-function modeling· 1 Approach:statistical model· 1

Frequent Co-Authors

Aravindh NagarajaniD· 1 shared Arjen ten HaveiD· 1 shared Brian Keith KennedyiD· 1 shared Charles D. JohnsoniD· 1 shared Courtney Roberts· 1 shared David W. ThreadgilliD· 1 shared Heidi M. BlankiD· 1 shared Helene L. Andrews‐PolymenisiD· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Aravindh NagarajanORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJan 12, 2024

Late-life dietary folate restriction reduces biosynthetic processes without compromising healthspan in mice

Heidi M. Blank, Staci E. Hammer, Laurel Boatright…·Michael Polymenis

This study shows that reducing folate intake in aged mice decreases biosynthetic processes but does not compromise healthspan, suggesting age-dependent benefits of folate restriction.

DOI 10.1101/2024.01.12.575290

mouseexperimental assay

𝕏 PostBluesky

BioinformaticsPLoS ONEPeer-reviewedMar 26, 2018

HMMER Cut-off Threshold Tool (HMMERCTTER): Supervised Classification of Superfamily Protein Sequences with a reliable Cut-off Threshold

Inti Anabela Pagnuco, Maria Victoria Revuelta, Hernán Gabriel Bondino…·Arjen ten Have

HMMERCTTER improves protein superfamily classification by introducing a reliable score cut-off threshold using high-quality training data and iterative sequence inclusion.

23 citations

protein sequencestatistical model

𝕏 PostBluesky