Author

Izumi de los Rios Kobara

Stanford MedicineORCID 0000-0002-6479-110XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Catherine A. BlishiD· 2 shared Aaron J. WilkiD· 1 shared Andra L. BlomkalnsiD· 1 shared Angela J. RogersiD· 1 shared Camilo A. EspinosaiD· 1 shared Hannah L. ItelliD· 1 shared Julie M. OverbaughiD· 1 shared Kari Christine NadeauiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Catherine A. BlishORCID

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2 papers

Recent·Most cited

Viral load-driven systemic immune exhaustion is an enabler of antibody breadth in HIV infection

Izumi de los Rios Kobara, Uma M. Mangalanathan, Soneida DeLine-Caballero, Kassandra Pinedo, Mikayla A. Stabile, Camilo A. Espinosa, Hannah L. Itell, Vrasha Chohan, Raymond Scott McClelland, Kishorchandra Mandaliya, Julie M. Overbaugh, Catherine A. Blish

The paper identifies viral load-driven immune exhaustion as a factor enabling antibody breadth in HIV infection by analyzing longitudinal data from a Kenyan cohort.

bioRxiv · Jun 17, 2026 · PreprintImmunology

Interferon-mediated NK cell activation is associated with limited neutralization breadth during SARS-CoV-2 infection

Izumi de los Rios Kobara, Radeesha Jayewickreme, Madeline J. Lee, Aaron J. Wilk, Stanford COVID-19 Biobank, Andra L. Blomkalns, Kari Christine Nadeau, Samuel S. Yang, Angela J. Rogers, Catherine A. Blish

The paper shows that NK cell activation during SARS-CoV-2 infection correlates with reduced neutralization breadth of antibodies.

Nature Immunology · Nov 21, 2025Peer-reviewedImmunology