Katharina Becker

This study examines VPA-induced changes in dorsal forebrain organoids using multiomics approaches, revealing disruptions in ECM and microenvironment signaling.

This study compares two single-cell RNA-sequencing multiplexing techniques, 10x and Parse, on cerebellar organoids, finding similar cellular diversity but differences in transcript capture and cell stress.

This study develops human organoid models of PCH2a to investigate brain region-specific pathology, finding size reductions in cerebellar organoids and altered proliferation kinetics.

This study uses a human 3D organoid model to show that maternal immune activation increases radial glia cell vulnerability and identifies species-specific gene responses linked to ASD risk.