Author

Christina Maree Buchanan

Auckland City HospitalORCID 0000-0002-6482-3474Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Chris KayiD· 1 shared Emily M. HarveyiD· 1 shared Glen Lester SequieraiD· 1 shared Hailey Findlay BlackiD· 1 shared Huu Phuc NguyeniD· 1 shared Inês Caldeira BrásiD· 1 shared Jessica Q. DawsoniD· 1 shared Kert MätlikiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Chris KayORCID

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1 paper

Recent·Most cited

Loss of interruption in the HTT CAG repeat is associated with increased somatic expansion and loss of medium spiny neurons in HD

Chris Kay, Jessica Q. Dawson, Kert Mätlik, Hailey Findlay Black, Emily M. Harvey, Stephanie Bortnick, Kyla Javier, Christina Maree Buchanan, Tanushri Soomarooah, Inês Caldeira Brás, Glen Lester Sequiera, Mahmoud A. Pouladi, Larissa Arning, Huu Phuc Nguyen, Richard H Roxburgh, , Michael R. Hayden

The paper shows that loss of interruption in HTT CAG repeats increases somatic expansion and MSN loss in HD, with greater effects in patients with CAG-CCG LOI.

bioRxiv · Mar 5, 2026 · PreprintNeuroscience