NeurosciencebioRxivPreprint
Loss of interruption in the HTT CAG repeat is associated with increased somatic expansion and loss of medium spiny neurons in HD
Chris Kay, Jessica Q. Dawson, Kert Mätlik…·Michael R. Hayden
The paper shows that loss of interruption in HTT CAG repeats increases somatic expansion and MSN loss in HD, with greater effects in patients with CAG-CCG LOI.
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