Dmitri S. Kudryashov

This paper identifies plastins as novel cytoskeletal pH sensors that reduce F-actin bundling at alkaline pH, affecting actin dynamics and potentially contributing to cancer progression.

The paper shows that actin-specific toxins from different bacteria inhibit each other's ability to disrupt the host actin cytoskeleton, revealing a mechanism of bacterial competition.

This study shows that Salmonella effector SipA stabilizes F-actin through a unique binding mechanism, similar to inorganic phosphate and phalloidin, enhancing toxin effects while avoiding host detection.

This study identifies MavH as a Legionella effector that promotes membrane-dependent actin polymerization by interacting with PI(3)P and host actin capping proteins.