Author

Yusha Wang

Zhejiang UniversityORCID 0000-0002-6507-5658Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:variant calling· 3 Assay:long-read sequencing· 2 Organism:human· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Ruikai Jia· 3 shared Xiaoshu Ma· 3 shared Changming ZhangiD· 1 shared Guo LiiD· 1 shared Hua Ye· 1 shared Hua YeiD· 1 shared Hua YeiD· 1 shared Hua ZhongiD· 1 shared

Activity by Year

2024-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersMolecular Biology

Ruikai Jia

Mutual co-authors in cluster

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4 papers

Recent·Most cited

IRAK2 deficiency causes a new immune dysregulation disorder

Yudie Fei, Lin Liu, Shuangyue Ma, Shihao Wang, Meiping Lu, Jing Xue, Ying Jin, Yusha Wang, Xiangwei Sun, Xiang Chen, Xu Han, Changming Zhang, Guo Li, Jiahui Zhang, Hua Zhong, , Zhihong Liu

IRAK2 deficiency causes immune dysregulation by disrupting TLR signaling and activating type I interferon responses in monocyte-macrophage lineage.

medRxiv · Oct 21, 2024 · PreprintGenetic & Genomic Medicine

A method for filtering abnormal modified base calling in Oxford Nanopore Technologies sequencing

Ruikai Jia, Yusha Wang, Hua Ye, Xiaoshu Ma

The paper introduces a method to filter abnormal modified base calling in Oxford Nanopore Technologies sequencing, improving accuracy and reducing the need for secondary sequencing.

Journal of Bioinformatics and Systems Biology · Jan 1, 2024Peer-reviewedBioinformatics

Direct Pacbio sequencing methods and applications for different types of DNA sequences

Yusha Wang, Xiaoshu Ma, Lei Yang, Hua Ye, Ruikai Jia

This study evaluates PacBio sequencing for direct, full-length resolution of complex DNA sequences, finding it effective for high GC, poly, and repeat sequences like rAAV without pre-fragmentation.

Archives of Microbiology & Immunology · Jan 1, 2024Peer-reviewedMolecular Biology

A new method and application of PacBio sequencing for low copy and difficulty preparation plasmids.

Xiaoshu Ma, Yusha Wang, Ruikai Jia, Hua Ye

This paper presents a method to improve PacBio sequencing of low-copy plasmids using Phi29 polymerase amplification and a plasmid-free sequencing approach.

Journal of Bioinformatics and Systems Biology · Jan 1, 2024Peer-reviewedMolecular Biology