Author

Patrick C. Chang

University of California, Los AngelesORCID 0000-0002-6510-9571Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Anthony AzzuniD· 1 shared Christopher SeetiD· 1 shared Claire EngstromiD· 1 shared Donald B. KohniD· 1 shared Gay M. CrooksiD· 1 shared Hanna K. A. MikkolaiD· 1 shared J. LaGosh· 1 shared Lindsay E. LathropiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Anthony AzzunORCID

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1 paper

Recent·Most cited

Stage-specific CAR-mediated signaling generates naive-like, TCR-null CAR T cells from induced pluripotent stem cells

Sang Pil Yoo, Xuegang Yuan, Claire Engstrom, Patrick C. Chang, Suwen Li, Lindsay E. Lathrop, J. LaGosh, Satvik Saripalli, Anthony Azzun, Vincenzo Calvanese, Hanna K. A. Mikkola, Christopher Seet, Donald B. Kohn, Gay M. Crooks

This study generates TCR-null CAR T cells from iPSCs by controlling CAR signaling stages, resulting in naive-like cells with enhanced cytotoxicity.

bioRxiv · Nov 25, 2024 · PreprintBioengineering