Author

J. LaGosh

University of California, Los Angeles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Aeowynn J. CoakleyiD· 1 shared Allison Rattray· 1 shared Anthony AzzuniD· 1 shared Bérénice Anath BenayouniD· 1 shared Bert M. VerheijeniD· 1 shared Biao HuangiD· 1 shared Christopher SeetiD· 1 shared Claire Chung· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Aeowynn J. CoakleyORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Stage-specific CAR-mediated signaling generates naive-like, TCR-null CAR T cells from induced pluripotent stem cells

Sang Pil Yoo, Xuegang Yuan, Claire Engstrom, Patrick C. Chang, Suwen Li, Lindsay E. Lathrop, J. LaGosh, Satvik Saripalli, Anthony Azzun, Vincenzo Calvanese, Hanna K. A. Mikkola, Christopher Seet, Donald B. Kohn, Gay M. Crooks

This study generates TCR-null CAR T cells from iPSCs by controlling CAR signaling stages, resulting in naive-like cells with enhanced cytotoxicity.

bioRxiv · Nov 25, 2024 · PreprintBioengineering

The fidelity of transcription in human cells

Claire Chung, Bert M. Verheijen, Xinmin Zhang, Biao Huang, Aeowynn J. Coakley, Eric G. McGann, E. Wade, Olivia Dinep-Schneider, J. LaGosh, Maria‐Eleni Anagnostou, Stephen Simpson, Kelly Thomas, Mimi Ernst, Allison Rattray, Michael Lynch, , Marc Vermulst

The paper estimates transcription fidelity in human cells, identifies factors controlling its accuracy, and links transcription errors to Alzheimer's disease progression.

Proceedings of the National Academy of Sciences · Jan 25, 2023Peer-reviewedGenetics