Brian Metscher

This paper identifies oxygen as a developmental switch regulating apoptosis in heart evolution and congenital defects, linking oxygen levels to heart structure and disease.

The paper describes the anatomical development of the conus arteriosus in Bufo bufo tadpoles, showing early formation of structures supporting pulmonary blood separation before lung appearance.

The paper introduces a simple lead(II) acetate staining method for microCT-based 3D histology that enhances nuclear contrast without requiring traditional staining or drying.