Pharmacology & ToxicologybioRxivPreprint
Angiotensin-(1-5) is a Potent Endogenous Angiotensin AT2-Receptor Agonist
Igor Maciel Souza Silva, A. Augusto Peluso, Khalid Elsaafien…·U. Muscha Steckelings
This study identifies angiotensin-(1-5) as a potent endogenous agonist of the AT2-receptor, showing its ability to increase nitric oxide release and lower blood pressure through AT2R-mediated mechanisms.