Eric G. Krause

This study identifies TREM2 as a regulator of myeloid cell function and immune dysregulation in pulmonary hypertension, showing its role in disease progression and potential as a therapeutic target.

This study identifies vagal afferents expressing the oxytocin receptor that mediate mechanosensation of the heart and gut, leading to hypometabolism and vigilance in mice.

This study identifies angiotensin-(1-5) as a potent endogenous agonist of the AT2-receptor, showing its ability to increase nitric oxide release and lower blood pressure through AT2R-mediated mechanisms.

The paper identifies lateralized vagal sensory neurons with distinct roles in satiety and food preference, revealing asymmetrical gut-brain circuits that control feeding behavior.

This study shows that dendritic membrane resistance in oxytocinergic magnocellular neurons modulates activity-induced calcium influx, impacting central oxytocin release.

The paper shows that central and peripheral GLP-1 systems independently suppress eating, and PPGNTS neuron activation addsitively enhances this effect with GLP-1 agonists.

This study shows that endogenous oxytocin inhibits hypothalamic CRH neurons during acute hypernatremia, reducing stress responsiveness through Oxtr-dependent mechanisms.

This study identifies macrophage AT2R activation as a key driver of neuropathic pain through ROS/NO-mediated TRPA1 activation in sensory neurons.