Author

Khalid Elsaafien

Georgia State UniversityORCID 0000-0001-9581-918XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Annette D. de KloetiD· 2 shared Eric G. KrauseiD· 2 shared A. Augusto PelusoiD· 1 shared André Felipe RodriguesiD· 1 shared Antonina L. NazarovaiD· 1 shared Arkadiusz NawrockiiD· 1 shared Caitlin Baumer-HarrisoniD· 1 shared Colin SumnersiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Annette D. de KloetORCID

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2 papers

Recent·Most cited

Mechanosensation of the heart and gut elicits hypometabolism and vigilance in mice.

Karen A. Scott, Yalun Tan, Dominique N. Johnson, Khalid Elsaafien, Caitlin Baumer-Harrison, Rebeca Méndez‐Hernández, Matthew K. Kirchner, Sophia A. Eikenberry, M. Jessica, Javier Eduardo Stern, Guillaume de Lartigue, Annette D. de Kloet, Eric G. Krause

This study identifies vagal afferents expressing the oxytocin receptor that mediate mechanosensation of the heart and gut, leading to hypometabolism and vigilance in mice.

Nature Metabolism · Jan 17, 2025Peer-reviewedNeuroscience

Angiotensin-(1-5) is a Potent Endogenous Angiotensin AT2-Receptor Agonist

Igor Maciel Souza Silva, A. Augusto Peluso, Khalid Elsaafien, Antonina L. Nazarova, Kasper Bostlund Assersen, Lucas Rodrigues‐Ribeiro, Mazher Mohammed, André Felipe Rodrigues, Arkadiusz Nawrocki, Lene Andrup Jakobsen, Pia Jensen, Annette D. de Kloet, Eric G. Krause, Mark P. Del Borgo, Ivan O. Maslov, , U. Muscha Steckelings

This study identifies angiotensin-(1-5) as a potent endogenous agonist of the AT2-receptor, showing its ability to increase nitric oxide release and lower blood pressure through AT2R-mediated mechanisms.

bioRxiv · Apr 5, 2024 · PreprintPharmacology & Toxicology