Kourosh Salehi‐Ashtiani

Coupling of oceanographic state to the dark proteome: a foundation for genome-informed marine productivity modeling

The paper uses a protein language model to analyze proteomic data and shows that underrepresented protein families in reference databases are strongly coupled to oceanographic conditions.

Conserved metabolic vulnerabilities across pathogenic coronaviruses nominate host-directed therapeutic targets

The paper identifies conserved metabolic vulnerabilities across SARS-CoV, SARS-CoV-2, and MERS-CoV using transcriptomic data and metabolic models, revealing druggable host targets.

Earth-Observation and Environmental Vision Transformers Reveal Genome-Environment Associations in Macroalgae

The paper identifies genome-environment associations in macroalgae by integrating remote sensing data with deep learning to uncover genomic signatures of ecological adaptation.

Time-Resolved Transcriptomics Reveal Spliceosomal Disruption and Senescence Pathways in Crocin-Treated Hepatocellular Carcinoma Cells

This study uses time-resolved transcriptomics to show crocin disrupts the spliceosome and activates senescence pathways in hepatocellular carcinoma cells, with dose-dependent effects on gene expression and splicing.

Multi-omics decipher the molecular mechanisms driving high-lipid production in an artificially-evolved Chlamydomonas mutant

The paper identifies mutations and multi-omic changes in a Chlamydomonas mutant (H5) that enhance lipid production without affecting growth.

A near telomere-to-telomere phased reference assembly for the male mountain gorilla

The paper presents a high-quality, near telomere-to-telomere, haplotype-phased reference genome for a male mountain gorilla using long-read sequencing technologies.

A high-quality genome assembly and annotation of the gray mangrove, Avicennia marina

This paper presents a high-quality chromosome-level genome assembly and annotation of the gray mangrove, identifying candidate genes for local adaptation.