New alleles of Arabidopsis BIK1 reinforce its predominant role in pattern-triggered immunity and caution interpretations of other reported functions
Beibei Song, Sera Choi, Liang Kong, Sung-Il Kim, Judith Fliegmann, Xiuming Li, Yong Gao, Thomas A. DeFalco, Meijuan Hu, Meng Li, Yan Zhao, Hongze Wang, Shengwei Ma, Libo Shan, Thorsten Nürnberger, , Jian-Min Zhou
The paper generates new alleles of BIK1 and PBL1 using CRISPR-Cas9 and shows their central role in pattern-triggered immunity, while highlighting pleiotropic effects of T-DNA insertions.
bioRxiv · Jun 2, 2025Plant Biology