Thorsten Nürnberger

Small Molecule Binding to EDS1/PAD4 in LRR-RP-Mediated Pattern-Triggered Immunity

The paper identifies small molecule binding to EDS1 and PAD4 as critical for LRR-RP-mediated PTI, with distinct roles in early and late immune responses.

β-sheet stabilization of the island domain underlies ligand-induced LRR-RP activation of plant immune signaling

This paper identifies a β-sheet stabilization mechanism in the island domain of LRR-RPs that mediates ligand binding and co-receptor recruitment, revealing insights into plant immune signaling activation.

New alleles of Arabidopsis BIK1 reinforce its predominant role in pattern-triggered immunity and caution interpretations of other reported functions

The paper generates new alleles of BIK1 and PBL1 using CRISPR-Cas9 and shows their central role in pattern-triggered immunity, while highlighting pleiotropic effects of T-DNA insertions.

The receptor-like kinases BIR1 and BIR3 modulate antiviral resistance by different mechanisms

This study identifies distinct roles of BIR1 and BIR3 in modulating antiviral resistance in Arabidopsis through different molecular mechanisms.

Enhancing plant broad-spectrum resistance through engineered pattern recognition receptors

This study engineers pattern recognition receptors to enhance broad-spectrum resistance in plants, showing improved efficacy in tomato, rice, and poplar.

Arabidopsis WALL-ASSOCIATED KINASES are not required for oligogalacturonide-induced signaling and immunity

This study shows that Arabidopsis WAKs are not required for oligogalacturonide-induced signaling and immunity.

A set of Arabidopsis genes involved in the accommodation of the downy mildew pathogen Hyaloperonospora arabidopsidis

The paper identifies Arabidopsis genes involved in accommodating the downy mildew pathogen Hpa, showing their role in haustorial maintenance and pathogen accommodation.

The fungal ligand chitin directly binds and signals inflammation dependent on oligomer size and TLR2

This study identifies chitin oligomers as the smallest immunologically active motif and TLR2 as the primary receptor for chitin, showing size-dependent signaling and therapeutic potential.