Author

Lauren M. Cozzens

University of Colorado AnschutzORCID 0000-0002-6545-683XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alan M. ElderiD· 2 shared Traci Renae LyonsiD· 2 shared Alexandria R Becks· 1 shared Brendan Hinckley· 1 shared Heather R. FairchildiD· 1 shared Jill E. SlanskyiD· 1 shared Kelsey T. KinesiD· 1 shared Pepper S. SchediniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersDevelopmental Biology

Alan M. ElderORCID

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2 papers

Recent·Most cited

SOX9 and SEMA7A regulate cell plasticity in the postpartum mammary gland with implications for breast cancer

Lauren M. Cozzens, Brendan Hinckley, Alan M. Elder, Veronica M. Wessells, Sonali Jindal, Pepper S. Schedin, Virginia F. Borges, Traci Lyons

This study identifies SOX9 and SEMA7A as regulators of cell plasticity in postpartum mammary glands and links their dysregulation to breast cancer progression and metastasis.

bioRxiv · May 18, 2026 · PreprintDevelopmental Biology

Semaphorin7A and PD-L1 cooperatively drive immunosuppression during mammary involution and breast cancer

Alan M. Elder, Heather R. Fairchild, Kelsey T. Kines, Lauren M. Cozzens, Alexandria R Becks, Jill E. Slansky, Steven Michael Anderson, Traci Renae Lyons

This study shows that SEMA7A promotes PD-L1 expression in mammary tissue during involution and in tumors, and a SEMA7A-targeting antibody reduces tumor growth and restores T cell function.

Cell Reports · May 1, 2025Peer-reviewedCancer Biology